Tag: colchicine macrolide interaction

Colchicine and Macrolides: How Drug Interactions Can Cause Life-Threatening Toxicity

Colchicine and Macrolides: How Drug Interactions Can Cause Life-Threatening Toxicity

Colchicine can be life-saving, but combining it with macrolides like clarithromycin can cause deadly toxicity. Learn how CYP3A4 and P-gp inhibition leads to dangerous drug interactions-and what to do to stay safe.